ECHA Guidance on Annex VIII to the CLP Regulation (UFI notifications) – New Version 6.0
Following the publication of Regulation (EU) 2024/2865, which introduces substantial amendments to the CLP Regulation, ECHA has revised the guidance document on Annex VIII
28 Oct 2025The European Chemicals Agency (ECHA) has published Version 6.0 of its Guidance on Annex VIII to the CLP Regulation. The document provides updated clarifications on Poison Centre Notifications and UFI codes to be submitted to the competent authorities of each Member State for mixtures classified as hazardous to human health and/or physical hazards.
This new edition introduces several clarifications and structural improvements aimed at simplifying readability and removing repetitive content. In particular, ECHA has updated the guidance to reflect regulatory changes and the evolution of practical interpretations, especially regarding distribution activities, use types and the compliance deadlines that have now expired.
Key updates include:
- Revision of Section 1 (Introduction), incorporating the new provisions and removing references to transitional periods.
- Updates to definitions and abbreviations (Section 2).
- Reorganization of Section 3 (Obligations), with reduced references to Article 4(10) and additional clarifications on interpretative differences among Member States.
- Improved readability in the sections dedicated to the UFI code, the submission of information and the management of Mixtures in Mixture (MiM).
- Updates to the rules concerning post-submission changes, in line with the latest legislative revisions.
The guidance continues to be an essential practical reference for manufacturers, importers, downstream users and distributors responsible for submitting harmonised information to poison centres under Article 45 and Annex VIII of the CLP Regulation.
However, ECHA emphasises that the document does not replace the legal text of the CLP Regulation, but rather facilitates its correct practical application. Operators remain responsible for ensuring the compliance and accuracy of the information provided.
For companies, this update offers a useful opportunity to review internal notification and labelling procedures, ensuring that the information submitted aligns with the latest technical and operational requirements.